Pregnancy is a wonderfully complicated process through which the body of a woman facilitates the development of new life. However, on rare occasions, even with a healthy embryo and the development of apparently optimal conditions, the body may reject the pregnancy, resulting in implantation failure, early miscarriage, or recurrent pregnancy loss. This is an emotionally traumatising and confusing process for couples attempting to conceive.

We are aware of the amount of pain involved in experiencing repeated pregnancy losses at Maaeri Fertility & IVF Centre. This blog examines the medical causes of why the body of a woman may reject a pregnancy and how it can be enhanced to ensure that there is a successful outcome.

Understanding Pregnancy Rejection

Pregnancy rejection is commonly used to refer to the cases when:

• The implanted embryo does not take place in the womb

• The pregnancy usually miscarries early (prematurely, before 12 weeks)

• The pregnancy is not supported by the immune system or the uterine environment

Now, we can have a closer look at the potential causes.

1. Immunological Factors

An essential role in pregnancy is played by the immune system. Although the embryo has foreign (paternal) genes, a strong immune system accepts it and helps it. However, in other women, pregnancy rejection could be a result of autoimmune or alloimmune disorders.

• High NK cells can destroy the embryo, thinking it is an enemy.

• The antiphospholipid syndrome (APS) may result in blood clots within the placenta that cause miscarriage.

• Incompatibility with the HLA of the parents may also affect the immune response towards the embryo.

2. Hormonal Imbalance

Implantation and maintenance of pregnancy require a well-balanced hormonal environment. The uterine lining and embryo development may be interfered with by low progesterone levels, thyroid problems, or high levels of prolactin.

Maaeri provides top notch fertility treatment in Noida with regularly monitor the hormone levels to make sure that the uterus is open and friendly during the implantation window.

3. Poor Endometrial Receptivity

Implantation can fail even with a healthy embryo if the uterus lining (endometrium) is too thin or inflamed or not coordinated with the growth of the embryo. This has been referred to as receptivity mismatch.

Such complex tests as the Endometrial Receptivity Array (ERA) can allow us to pinpoint the exact window of implantation, giving us a better chance of success with IVF.

4. Genetic and Chromosomal Abnormalities

In case the embryo has some chromosomal abnormalities, the body can automatically eliminate the pregnancy at the very beginning to avoid further complications. This is among the frequent causes of the first-trimester miscarriage.

We provide Preimplantation Genetic Testing (PGT-A) in the IVF cycles to make sure that only genetically normal embryos are transferred.

5. Structural Issues in the Uterus

Dysfunction of the uterus, such as:

• Fibroids

• Polyps

• Septate uterus

• Asherman syndrome (adhesions)

It may disrupt implantation and cause miscarriage. We detect and rectify these conditions through the use of 3D ultrasounds and hysteroscopy, and then the transfer planning is done in Maaeri.

6. Lifestyle and Environmental Factors

Smoking, high stress, obesity, too much alcohol or caffeine, and exposure to toxins are some of the factors that can have a deleterious impact on the immune response and the hormonal balance, leading to a failed pregnancy.

We assist our patients by providing individual preconception counselling and fertility-compatible lifestyle advice to maximise their opportunities.

What Can Be Done?

In the event that your body has rejected previous pregnancies or IVF procedures, then the solution lies in a well-documented diagnosis and a special fertility treatment in Noida. At Maaeri, we offer:

Special diagnostic testing (immune panels, hormonal mapping, uterine scans)

• Immuno tablets, such as intralipids or steroids, in case of necessity

• Lifestyle and nutritional coaching

• Mental and emotional well-being, supportive counselling

Suggest to Read :- What Happens During Embryo Transfer? Step by Step

Final Thoughts

A woman conceives and her body reacts badly to it due to a countless number of things in her body that we are never able to see, but through medical care, most of the issues can be diagnosed, and the solution found. You are not the first one, and you still can have a child.

We are combining the best in reproductive science with the best in caring to assist every couple in getting the best possible chance of success at Maaeri Fertility & IVF Centre.